Proviron is a hormone preparation with low androgenic activity. Proviron is used in bodybuilding over anabolic steroids for various purposes.
Available in tablet form, mostly 25mg. It is an aromatase inhibitor, that is, it prevents the conversion of steroids to estrogen in the body. Proviron prevents gynecomastia, fluid retention, female fat deposits and other estrogenic side effects.

It does not affect the body’s own production of testosterone (in high doses it can suppress it), but it does help increase the concentration of free testosterone in the blood as it blocks the activity of hormone-binding globulin sexually. These properties make Proviron an attractive remedy during the cycle.

It is often used as part of post-cycle therapy, although its suitability is questionable as it lacks the ability to restore endogenous testosterone secretion.

Application in the world of bodybuilding

world of bodybuilding

The first type of use is the result of its structure. The reduced mesterolone (5-alpha) formula is not able to be converted to estrogen. However, it has a higher affinity for the aromatase enzyme (which converts testosterone to estrogen) than testosterone. This means that when taken together with testosterone or another aromatase compound, estrogen is prevented from spreading because it is tightly bound to the aromatase enzyme, which prevents these steroids from being converted to estrogen. Therefore, the use of Mesterolone offers great benefits: it reduces estrogenic side effects and water retention seen with other steroids; In addition, it requires a bit of effort. It can also be assumed that this drug can actually desensitize estrogen receptors, doubling its effectiveness in mitigating circulating estrogen levels.

The second application is based on expanding the potential for testosterone. Testosterone in the body of a healthy person is usually inactive. 97-98% of testosterone is bound to sex hormone binding globulin (SHBG) and albumin, two proteins. In this form, testosterone is mostly inactive. However, like the aromatase enzyme, dihydrotestosterone has a greater affinity for these proteins than testosterone. Therefore, when mesterolone binds to globulin and albumin, there is a large amount of free testosterone left to perform anabolic processes such as protein synthesis. And it helps to increase performance. There is also another part of the equation that is ineffective in itself: the confusion of these proteins is not converted into an androgen receptor.


Third, mesterolone is added in pre-competition cycles to increase muscle stiffness and bulk. Probably due to decreased circulating estrogen levels; Perhaps due to the down-regulation of the estrogen receptor in the muscle tissues, the water balance in the body is reduced, giving the user the visual effect of stiff, slim and quality muscles. Proviron is often used casually among bodybuilders, but even actors and models use it again and again to get in shape the last day before filming. Like the other methylated dihydrotestosterone compound, Drostanolone, Mesterolone is particularly potent at achieving this effect.

Finally, Proviron is used during the cycle of hormones like Nandrolone with a weak androgenic effect. Perhaps the abbreviated formula 5-alpha in this case is different from dihydrotestosterone. Compounds like trenbolone and nandrolone are known to reduce libido. The logical result is the restriction of the athlete’s sexuality. DHT plays a key role in this process and is therefore used in conjunction with such steroids to reduce or diminish this annoying side effect. Proviron is also commonly prescribed by doctors to people with low testosterone levels or patients with chronic impotence. It is not perceived as a strong anabolic. It will do the job just as well, if not better than other anabolic steroids. Proviron is less likely to be abused, making it a favorite in medical practice.

Mesterolone is preferred by many athletes because it has almost no side effects in men. In high doses, it can cause virilization symptoms in women.